ProfileGDS5268 / 1559595_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 28% 26% 31% 24% 28% 28% 27% 31% 24% 25% 28% 31% 30% 32% 35% 27% 33% 26% 25% 30% 29% 28% 26% 28% 28% 27% 27% 23% 34% 40% 28% 26% 34% 26% 30% 25% 28% 25% 27% 34% 24% 29% 30% 29% 22% 26% 32% 28% 31% 26% 30% 25% 26% 26% 28% 25% 30% 28% 26% 27% 23% 30% 29% 25% 32% 26% 27% 28% 24% 25% 25% 26% 25% 29% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a20.801528
GSM386436Untreated HCT116 cells, replicate b20.364326
GSM386437Untreated HCT116 cells, replicate d23.249231
GSM386438Untreated HCT116 cells, replicate e19.496624
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b21.470728
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d20.874228
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e20.277327
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f23.481331
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a19.623824
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b19.546525
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d21.556728
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e23.044731
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a22.466830
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c25.338832
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e26.005835
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f21.61327
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a24.307433
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c19.348426
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e19.437725
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f22.137430
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b22.086129
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c20.906428
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d19.914726
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f21.245728
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b22.113528
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c20.498327
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d20.97327
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f18.716223
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c25.3734
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d30.714640
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e21.410528
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f20.677626
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a26.652734
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b20.273126
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e22.859830
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f20.171225
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b22.006528
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c20.342825
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d21.392127
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e25.453234
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c19.466224
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d22.208329
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e23.243530
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f21.886329
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b18.76722
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d20.188826
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e23.743232
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f22.010228
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b23.684531
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c21.587626
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f22.680430
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a20.030625
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b21.112426
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d20.928826
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e21.986428
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b20.084425
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d23.162630
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a21.174528
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d21.288426
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e20.575727
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f18.594623
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a22.24830
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c22.64229
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f19.659125
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b24.519132
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e20.801126
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b21.812127
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c23.502228
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f19.549524
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c20.310625
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d20.7225
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b20.505726
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e20.784625
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f22.64229