ProfileGDS5268 / 1558293_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 9% 8% 8% 9% 11% 10% 10% 9% 6% 5% 10% 7% 8% 10% 7% 10% 9% 16% 12% 14% 23% 21% 28% 21% 10% 14% 13% 12% 5% 10% 8% 6% 9% 11% 7% 8% 6% 6% 9% 10% 19% 13% 20% 23% 9% 6% 7% 6% 6% 11% 7% 9% 6% 6% 8% 5% 10% 18% 11% 15% 13% 8% 10% 6% 5% 3% 2% 4% 2% 6% 5% 15% 11% 12% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a12.84969
GSM386436Untreated HCT116 cells, replicate b12.66998
GSM386437Untreated HCT116 cells, replicate d12.93948
GSM386438Untreated HCT116 cells, replicate e12.98799
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b13.598811
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d13.139510
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e12.90510
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f12.90879
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a11.67976
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b11.20465
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d13.262910
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e11.97287
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a12.57558
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c13.912810
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e12.04797
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f13.730610
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a13.03279
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c15.193316
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e14.080812
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f14.66814
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b19.175623
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c17.553721
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d20.86828
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f17.75921
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b13.701610
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c14.936114
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d14.827813
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f14.013112
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c11.4355
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d13.279910
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e12.49428
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f12.15626
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a13.529
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b13.592311
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e12.35827
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f12.50088
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b11.9726
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c12.14486
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d13.02069
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e13.504510
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c16.689419
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d14.35713
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e17.916820
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f18.708923
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b13.12049
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d11.56866
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e12.30347
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f11.89236
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b12.17756
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c14.306411
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f12.3137
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a13.33729
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b12.03886
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d12.29246
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e12.60798
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b11.47965
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d13.553110
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a16.179418
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d14.01711
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e15.21715
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f14.410113
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a12.43078
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c13.510810
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f11.61316
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b11.66535
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e11.13413
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b10.24732
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c11.50414
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f10.34542
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c12.09026
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d11.81985
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b15.431615
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e14.032811
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f14.355512