ProfileGDS5268 / 1553145_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 28% 16% 28% 18% 21% 24% 21% 17% 16% 21% 25% 23% 20% 25% 13% 21% 22% 24% 16% 19% 22% 20% 22% 27% 26% 19% 20% 21% 18% 21% 21% 21% 23% 19% 18% 15% 18% 17% 14% 13% 18% 21% 22% 17% 21% 25% 20% 18% 23% 23% 20% 21% 18% 21% 23% 25% 18% 23% 17% 22% 24% 22% 22% 16% 22% 26% 16% 28% 20% 25% 16% 23% 25% 18% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a20.901728
GSM386436Untreated HCT116 cells, replicate b15.63416
GSM386437Untreated HCT116 cells, replicate d21.735328
GSM386438Untreated HCT116 cells, replicate e16.37818
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b17.678321
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d18.870524
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e17.412321
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f16.024117
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a15.697116
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b17.784321
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d19.634925
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e18.697423
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a17.55120
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c21.228525
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e14.25213
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f18.263721
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a18.088522
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c18.453524
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e15.635716
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f16.841619
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b18.694822
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c17.170720
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d18.165422
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f20.541627
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b20.960626
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c16.695219
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d17.540720
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f17.723721
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c16.714618
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d18.272321
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e17.66921
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f18.249721
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a19.662623
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b16.944819
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e16.821418
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f15.47615
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b16.729918
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c16.784617
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d14.744914
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e14.321713
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c16.476318
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d17.883421
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e18.58622
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f16.061417
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b18.118121
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d20.011725
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e17.455920
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f16.724818
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b19.234723
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c19.703123
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f17.569320
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a18.213321
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b16.969418
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d18.533621
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e19.149723
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b20.284125
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d16.814518
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a18.368723
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d16.684217
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e18.497222
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f19.328924
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a18.205322
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c18.937822
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f15.488716
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b18.914722
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e20.813326
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b16.501716
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c23.096228
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f17.944620
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c20.260925
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d15.928316
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b18.931923
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e20.647625
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f16.928418