ProfileGDS5242 / 8179167
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 66% 61% 41% 61% 52% 49% 48% 47% 43% 42% 39% 59% 48% 37% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 14.750566
GSM1248749naïve B cells CD40L/IL-21; donor 14.488661
GSM1248746naïve B cells CD40L alone; donor 23.770141
GSM1248750naïve B cells CD40L/IL-21; donor 24.478761
GSM1248747naïve B cells CD40L alone; donor 34.29152
GSM1248751naïve B cells CD40L/IL-21; donor 34.192349
GSM1248748naïve B cells CD40L alone; donor 44.026448
GSM1248752naïve B cells CD40L/IL-21; donor 43.975247
GSM1248753naïve B cells CD40L alone; AD-HIES pt 14.042943
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 13.926542
GSM1248754naïve B cells CD40L alone; AD-HIES pt 23.857939
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 24.451759
GSM1248755naïve B cells CD40L alone; AD-HIES pt 34.253448
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 33.819837