ProfileGDS5242 / 8176962
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 88% 90% 92% 89% 60% 55% 92% 92% 83% 82% 68% 81% 56% 66% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 16.189888
GSM1248749naïve B cells CD40L/IL-21; donor 16.509890
GSM1248746naïve B cells CD40L alone; donor 26.206992
GSM1248750naïve B cells CD40L/IL-21; donor 26.11589
GSM1248747naïve B cells CD40L alone; donor 34.505560
GSM1248751naïve B cells CD40L/IL-21; donor 34.404255
GSM1248748naïve B cells CD40L alone; donor 46.149992
GSM1248752naïve B cells CD40L/IL-21; donor 46.364492
GSM1248753naïve B cells CD40L alone; AD-HIES pt 15.223783
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 15.370382
GSM1248754naïve B cells CD40L alone; AD-HIES pt 24.806468
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 25.167881
GSM1248755naïve B cells CD40L alone; AD-HIES pt 34.476456
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 34.745666