ProfileGDS5242 / 8146837
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 30% 23% 36% 17% 10% 14% 9% 5% 10% 10% 4% 54% 6% 4% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 13.032430
GSM1248749naïve B cells CD40L/IL-21; donor 12.611323
GSM1248746naïve B cells CD40L alone; donor 23.589236
GSM1248750naïve B cells CD40L/IL-21; donor 22.530417
GSM1248747naïve B cells CD40L alone; donor 32.541110
GSM1248751naïve B cells CD40L/IL-21; donor 32.639214
GSM1248748naïve B cells CD40L alone; donor 42.15939
GSM1248752naïve B cells CD40L/IL-21; donor 41.49965
GSM1248753naïve B cells CD40L alone; AD-HIES pt 12.568110
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 12.284310
GSM1248754naïve B cells CD40L alone; AD-HIES pt 21.57014
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 24.305154
GSM1248755naïve B cells CD40L alone; AD-HIES pt 31.99576
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 31.6784