ProfileGDS5242 / 8133030
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 90% 93% 85% 92% 67% 62% 75% 85% 86% 78% 49% 48% 47% 51% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 16.387890
GSM1248749naïve B cells CD40L/IL-21; donor 16.837593
GSM1248746naïve B cells CD40L alone; donor 25.592485
GSM1248750naïve B cells CD40L/IL-21; donor 26.619292
GSM1248747naïve B cells CD40L alone; donor 34.704267
GSM1248751naïve B cells CD40L/IL-21; donor 34.609662
GSM1248748naïve B cells CD40L alone; donor 44.972375
GSM1248752naïve B cells CD40L/IL-21; donor 45.644985
GSM1248753naïve B cells CD40L alone; AD-HIES pt 15.400886
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 15.186478
GSM1248754naïve B cells CD40L alone; AD-HIES pt 24.210849
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 24.132248
GSM1248755naïve B cells CD40L alone; AD-HIES pt 34.199347
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 34.282551