ProfileGDS5242 / 8124440
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 67% 84% 74% 85% 30% 85% 57% 82% 35% 41% 30% 38% 41% 41% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 14.804667
GSM1248749naïve B cells CD40L/IL-21; donor 15.988184
GSM1248746naïve B cells CD40L alone; donor 25.001374
GSM1248750naïve B cells CD40L/IL-21; donor 25.780585
GSM1248747naïve B cells CD40L alone; donor 33.620830
GSM1248751naïve B cells CD40L/IL-21; donor 35.452985
GSM1248748naïve B cells CD40L alone; donor 44.306657
GSM1248752naïve B cells CD40L/IL-21; donor 45.462882
GSM1248753naïve B cells CD40L alone; AD-HIES pt 13.803135
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 13.9141
GSM1248754naïve B cells CD40L alone; AD-HIES pt 23.501730
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 23.845138
GSM1248755naïve B cells CD40L alone; AD-HIES pt 34.004741
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 33.952241