ProfileGDS5242 / 8115562
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 88% 83% 88% 92% 80% 73% 93% 88% 91% 90% 86% 81% 80% 64% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 16.216688
GSM1248749naïve B cells CD40L/IL-21; donor 15.838983
GSM1248746naïve B cells CD40L alone; donor 25.838388
GSM1248750naïve B cells CD40L/IL-21; donor 26.482992
GSM1248747naïve B cells CD40L alone; donor 35.133580
GSM1248751naïve B cells CD40L/IL-21; donor 34.977673
GSM1248748naïve B cells CD40L alone; donor 46.305893
GSM1248752naïve B cells CD40L/IL-21; donor 45.92188
GSM1248753naïve B cells CD40L alone; AD-HIES pt 15.726591
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 15.905890
GSM1248754naïve B cells CD40L alone; AD-HIES pt 25.597386
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 25.170181
GSM1248755naïve B cells CD40L alone; AD-HIES pt 35.212480
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 34.709464