ProfileGDS5242 / 8100251
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 90% 91% 68% 84% 39% 29% 74% 77% 61% 79% 49% 34% 15% 20% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 16.331290
GSM1248749naïve B cells CD40L/IL-21; donor 16.571691
GSM1248746naïve B cells CD40L alone; donor 24.782168
GSM1248750naïve B cells CD40L/IL-21; donor 25.714484
GSM1248747naïve B cells CD40L alone; donor 33.917739
GSM1248751naïve B cells CD40L/IL-21; donor 33.481129
GSM1248748naïve B cells CD40L alone; donor 44.949374
GSM1248752naïve B cells CD40L/IL-21; donor 45.169477
GSM1248753naïve B cells CD40L alone; AD-HIES pt 14.522361
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 15.245779
GSM1248754naïve B cells CD40L alone; AD-HIES pt 24.193549
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 23.722834
GSM1248755naïve B cells CD40L alone; AD-HIES pt 32.869915
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 33.067420