ProfileGDS5242 / 8089291
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 15% 23% 35% 40% 67% 56% 67% 34% 86% 80% 27% 64% 80% 65% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 12.225215
GSM1248749naïve B cells CD40L/IL-21; donor 12.605923
GSM1248746naïve B cells CD40L alone; donor 23.543535
GSM1248750naïve B cells CD40L/IL-21; donor 23.641640
GSM1248747naïve B cells CD40L alone; donor 34.702867
GSM1248751naïve B cells CD40L/IL-21; donor 34.412356
GSM1248748naïve B cells CD40L alone; donor 44.656767
GSM1248752naïve B cells CD40L/IL-21; donor 43.419334
GSM1248753naïve B cells CD40L alone; AD-HIES pt 15.360286
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 15.285680
GSM1248754naïve B cells CD40L alone; AD-HIES pt 23.333527
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 24.580864
GSM1248755naïve B cells CD40L alone; AD-HIES pt 35.212580
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 34.710865