ProfileGDS5242 / 8086482
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 65% 64% 59% 55% 46% 42% 57% 51% 49% 56% 53% 68% 50% 64% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 14.726465
GSM1248749naïve B cells CD40L/IL-21; donor 14.689664
GSM1248746naïve B cells CD40L alone; donor 24.457559
GSM1248750naïve B cells CD40L/IL-21; donor 24.204155
GSM1248747naïve B cells CD40L alone; donor 34.134646
GSM1248751naïve B cells CD40L/IL-21; donor 34.000542
GSM1248748naïve B cells CD40L alone; donor 44.325457
GSM1248752naïve B cells CD40L/IL-21; donor 44.143451
GSM1248753naïve B cells CD40L alone; AD-HIES pt 14.199449
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 14.393556
GSM1248754naïve B cells CD40L alone; AD-HIES pt 24.343953
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 24.720668
GSM1248755naïve B cells CD40L alone; AD-HIES pt 34.287550
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 34.70364