ProfileGDS5242 / 8083709
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 89% 95% 93% 96% 37% 63% 94% 95% 95% 95% 67% 81% 41% 54% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 16.274689
GSM1248749naïve B cells CD40L/IL-21; donor 17.372995
GSM1248746naïve B cells CD40L alone; donor 26.442593
GSM1248750naïve B cells CD40L/IL-21; donor 27.190496
GSM1248747naïve B cells CD40L alone; donor 33.848137
GSM1248751naïve B cells CD40L/IL-21; donor 34.635363
GSM1248748naïve B cells CD40L alone; donor 46.473894
GSM1248752naïve B cells CD40L/IL-21; donor 47.085895
GSM1248753naïve B cells CD40L alone; AD-HIES pt 16.17895
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 16.576295
GSM1248754naïve B cells CD40L alone; AD-HIES pt 24.781967
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 25.161181
GSM1248755naïve B cells CD40L alone; AD-HIES pt 34.017841
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 34.374354