ProfileGDS5242 / 8048647
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 62% 62% 50% 51% 57% 52% 45% 55% 41% 56% 56% 62% 63% 59% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 14.590862
GSM1248749naïve B cells CD40L/IL-21; donor 14.566462
GSM1248746naïve B cells CD40L alone; donor 24.121150
GSM1248750naïve B cells CD40L/IL-21; donor 24.059951
GSM1248747naïve B cells CD40L alone; donor 34.431657
GSM1248751naïve B cells CD40L/IL-21; donor 34.31552
GSM1248748naïve B cells CD40L alone; donor 43.921545
GSM1248752naïve B cells CD40L/IL-21; donor 44.281955
GSM1248753naïve B cells CD40L alone; AD-HIES pt 13.970441
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 14.402256
GSM1248754naïve B cells CD40L alone; AD-HIES pt 24.435556
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 24.519662
GSM1248755naïve B cells CD40L alone; AD-HIES pt 34.693763
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 34.538159