ProfileGDS5242 / 8042558
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 47% 41% 37% 39% 42% 44% 48% 35% 18% 40% 45% 50% 38% 42% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 13.812147
GSM1248749naïve B cells CD40L/IL-21; donor 13.489141
GSM1248746naïve B cells CD40L alone; donor 23.620837
GSM1248750naïve B cells CD40L/IL-21; donor 23.601239
GSM1248747naïve B cells CD40L alone; donor 34.005842
GSM1248751naïve B cells CD40L/IL-21; donor 34.042544
GSM1248748naïve B cells CD40L alone; donor 44.017548
GSM1248752naïve B cells CD40L/IL-21; donor 43.504535
GSM1248753naïve B cells CD40L alone; AD-HIES pt 13.124618
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 13.84540
GSM1248754naïve B cells CD40L alone; AD-HIES pt 24.058345
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 24.175150
GSM1248755naïve B cells CD40L alone; AD-HIES pt 33.910138
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 33.991542