ProfileGDS5242 / 8029978
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 40% 40% 51% 37% 61% 56% 38% 39% 27% 28% 50% 48% 60% 41% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 13.492840
GSM1248749naïve B cells CD40L/IL-21; donor 13.432540
GSM1248746naïve B cells CD40L alone; donor 24.142851
GSM1248750naïve B cells CD40L/IL-21; donor 23.523937
GSM1248747naïve B cells CD40L alone; donor 34.544761
GSM1248751naïve B cells CD40L/IL-21; donor 34.42756
GSM1248748naïve B cells CD40L alone; donor 43.696538
GSM1248752naïve B cells CD40L/IL-21; donor 43.635539
GSM1248753naïve B cells CD40L alone; AD-HIES pt 13.543627
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 13.366128
GSM1248754naïve B cells CD40L alone; AD-HIES pt 24.222950
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 24.134248
GSM1248755naïve B cells CD40L alone; AD-HIES pt 34.593860
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 33.971341