ProfileGDS5242 / 8009951
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 44% 46% 40% 34% 48% 41% 29% 38% 43% 50% 42% 55% 40% 41% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 13.707444
GSM1248749naïve B cells CD40L/IL-21; donor 13.751146
GSM1248746naïve B cells CD40L alone; donor 23.757940
GSM1248750naïve B cells CD40L/IL-21; donor 23.425434
GSM1248747naïve B cells CD40L alone; donor 34.175748
GSM1248751naïve B cells CD40L/IL-21; donor 33.955441
GSM1248748naïve B cells CD40L alone; donor 43.382829
GSM1248752naïve B cells CD40L/IL-21; donor 43.596738
GSM1248753naïve B cells CD40L alone; AD-HIES pt 14.03143
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 14.192150
GSM1248754naïve B cells CD40L alone; AD-HIES pt 23.945642
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 24.328155
GSM1248755naïve B cells CD40L alone; AD-HIES pt 33.989440
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 33.974941