ProfileGDS5242 / 7976642
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 57% 50% 67% 74% 97% 96% 87% 64% 97% 96% 92% 36% 97% 97% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 14.315857
GSM1248749naïve B cells CD40L/IL-21; donor 13.923750
GSM1248746naïve B cells CD40L alone; donor 24.749367
GSM1248750naïve B cells CD40L/IL-21; donor 25.065274
GSM1248747naïve B cells CD40L alone; donor 36.749397
GSM1248751naïve B cells CD40L/IL-21; donor 36.598196
GSM1248748naïve B cells CD40L alone; donor 45.694287
GSM1248752naïve B cells CD40L/IL-21; donor 44.595864
GSM1248753naïve B cells CD40L alone; AD-HIES pt 17.055697
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 16.612396
GSM1248754naïve B cells CD40L alone; AD-HIES pt 26.052792
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 23.798836
GSM1248755naïve B cells CD40L alone; AD-HIES pt 36.896597
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 36.938997