ProfileGDS5242 / 7946569
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 76% 82% 52% 70% 28% 18% 58% 58% 44% 40% 36% 36% 32% 32% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 15.324376
GSM1248749naïve B cells CD40L/IL-21; donor 15.777882
GSM1248746naïve B cells CD40L alone; donor 24.205552
GSM1248750naïve B cells CD40L/IL-21; donor 24.874670
GSM1248747naïve B cells CD40L alone; donor 33.557328
GSM1248751naïve B cells CD40L/IL-21; donor 32.943418
GSM1248748naïve B cells CD40L alone; donor 44.356758
GSM1248752naïve B cells CD40L/IL-21; donor 44.396958
GSM1248753naïve B cells CD40L alone; AD-HIES pt 14.072244
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 13.875840
GSM1248754naïve B cells CD40L alone; AD-HIES pt 23.733236
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 23.800336
GSM1248755naïve B cells CD40L alone; AD-HIES pt 33.680732
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 33.639932