ProfileGDS5242 / 7946561
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 13% 7% 12% 15% 20% 25% 10% 14% 13% 16% 20% 46% 20% 13% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 12.129513
GSM1248749naïve B cells CD40L/IL-21; donor 11.57427
GSM1248746naïve B cells CD40L alone; donor 22.25612
GSM1248750naïve B cells CD40L/IL-21; donor 22.424415
GSM1248747naïve B cells CD40L alone; donor 33.219720
GSM1248751naïve B cells CD40L/IL-21; donor 33.309625
GSM1248748naïve B cells CD40L alone; donor 42.186310
GSM1248752naïve B cells CD40L/IL-21; donor 42.294214
GSM1248753naïve B cells CD40L alone; AD-HIES pt 12.824913
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 12.740616
GSM1248754naïve B cells CD40L alone; AD-HIES pt 22.991920
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 24.094846
GSM1248755naïve B cells CD40L alone; AD-HIES pt 33.140120
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 32.591613