ProfileGDS5242 / 7935146
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 64% 56% 62% 66% 10% 19% 69% 55% 23% 23% 24% 21% 13% 12% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 14.650964
GSM1248749naïve B cells CD40L/IL-21; donor 14.266456
GSM1248746naïve B cells CD40L alone; donor 24.566862
GSM1248750naïve B cells CD40L/IL-21; donor 24.668966
GSM1248747naïve B cells CD40L alone; donor 32.526910
GSM1248751naïve B cells CD40L/IL-21; donor 32.987519
GSM1248748naïve B cells CD40L alone; donor 44.726569
GSM1248752naïve B cells CD40L/IL-21; donor 44.276555
GSM1248753naïve B cells CD40L alone; AD-HIES pt 13.370523
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 13.173123
GSM1248754naïve B cells CD40L alone; AD-HIES pt 23.186424
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 23.314121
GSM1248755naïve B cells CD40L alone; AD-HIES pt 32.687613
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 32.557212