ProfileGDS5242 / 7926805
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 28% 34% 8% 12% 9% 5% 11% 14% 6% 13% 8% 17% 4% 9% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 12.929628
GSM1248749naïve B cells CD40L/IL-21; donor 13.150534
GSM1248746naïve B cells CD40L alone; donor 21.86128
GSM1248750naïve B cells CD40L/IL-21; donor 22.185912
GSM1248747naïve B cells CD40L alone; donor 32.43729
GSM1248751naïve B cells CD40L/IL-21; donor 31.64425
GSM1248748naïve B cells CD40L alone; donor 42.301111
GSM1248752naïve B cells CD40L/IL-21; donor 42.341514
GSM1248753naïve B cells CD40L alone; AD-HIES pt 12.16436
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 12.525513
GSM1248754naïve B cells CD40L alone; AD-HIES pt 22.10268
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 23.159917
GSM1248755naïve B cells CD40L alone; AD-HIES pt 31.75074
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 32.30119