ProfileGDS5242 / 7920291
TitleInterleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients
OrganismHomo sapiens


donor 1 donor 2 donor 3 donor 4 patient 1 patient 2 patient 3 normal autosomal dominant hyper IgE syndrome CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation CD40L stimulation CD40L + IL21 stimulation GSM1248745 GSM1248749 GSM1248746 GSM1248750 GSM1248747 GSM1248751 GSM1248748 GSM1248752 GSM1248753 GSM1248756 GSM1248754 GSM1248757 GSM1248755 GSM1248758 37% 31% 36% 40% 59% 30% 22% 42% 40% 31% 56% 62% 68% 57% sort by individual sort by disease state sort by protocol Gene Expression Profile
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SampleTitleValueRank
GSM1248745naïve B cells CD40L alone; donor 13.378337
GSM1248749naïve B cells CD40L/IL-21; donor 12.995431
GSM1248746naïve B cells CD40L alone; donor 23.596736
GSM1248750naïve B cells CD40L/IL-21; donor 23.640440
GSM1248747naïve B cells CD40L alone; donor 34.478259
GSM1248751naïve B cells CD40L/IL-21; donor 33.557730
GSM1248748naïve B cells CD40L alone; donor 43.049722
GSM1248752naïve B cells CD40L/IL-21; donor 43.778942
GSM1248753naïve B cells CD40L alone; AD-HIES pt 13.961940
GSM1248756naïve B cells CD40L/IL-21; AD-HIES pt 13.528631
GSM1248754naïve B cells CD40L alone; AD-HIES pt 24.450356
GSM1248757naïve B cells CD40L/IL-21; AD-HIES pt 24.514862
GSM1248755naïve B cells CD40L alone; AD-HIES pt 34.820468
GSM1248758naïve B cells CD40L/IL-21; AD-HIES pt 34.492757