ProfileGDS5029 / 46270_at
TitleSW480 KRAS-mutant colorectal cancer cell line response to dual inhibition of tankyrase and MEK: time course
OrganismHomo sapiens


untreated DMSO MEK inhibitor tankyrase inhibitor tankyrase and MEK inhibitors control 4 hours 16 hours 4 hours 16 hours 4 hours 16 hours 4 hours 16 hours GSM1340521 GSM1340522 GSM1340523 GSM1340524 GSM1340531 GSM1340532 GSM1340527 GSM1340528 GSM1340535 GSM1340536 GSM1340525 GSM1340526 GSM1340533 GSM1340534 GSM1340529 GSM1340530 GSM1340537 GSM1340538 96% 95% 94% 94% 95% 94% 96% 96% 96% 96% 95% 94% 94% 94% 97% 96% 95% 95% sort by protocol sort by time Gene Expression Profile
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SampleTitleValueRank
GSM1340521parental biological replicate 11199.496
GSM1340522parental biological replicate 21138.995
GSM1340523DMSO 4h biological replicate 1990.694
GSM1340524DMSO 4h biological replicate 21030.894
GSM1340531DMSO 16h biological replicate 11088.295
GSM1340532DMSO 16h biological replicate 21046.394
GSM1340527MEKi 4h biological replicate 11296.196
GSM1340528MEKi 4h biological replicate 21385.796
GSM1340535MEKi 16h biological replicate 11252.596
GSM1340536MEKi 16h biological replicate 21246.696
GSM1340525TNKSi 4h biological replicate 11056.595
GSM1340526TNKSi 4h biological replicate 21030.994
GSM1340533TNKSi 16h biological replicate 195894
GSM1340534TNKSi 16h biological replicate 21042.694
GSM1340529Combo 4h biological replicate 1145597
GSM1340530Combo 4h biological replicate 21368.896
GSM1340537Combo 16h biological replicate 11117.495
GSM1340538Combo 16h biological replicate 21122.395