ProfileGDS5029 / 226847_at
TitleSW480 KRAS-mutant colorectal cancer cell line response to dual inhibition of tankyrase and MEK: time course
OrganismHomo sapiens


untreated DMSO MEK inhibitor tankyrase inhibitor tankyrase and MEK inhibitors control 4 hours 16 hours 4 hours 16 hours 4 hours 16 hours 4 hours 16 hours GSM1340521 GSM1340522 GSM1340523 GSM1340524 GSM1340531 GSM1340532 GSM1340527 GSM1340528 GSM1340535 GSM1340536 GSM1340525 GSM1340526 GSM1340533 GSM1340534 GSM1340529 GSM1340530 GSM1340537 GSM1340538 20% 26% 15% 24% 24% 33% 23% 6% 18% 22% 21% 15% 13% 19% 30% 30% 27% 21% sort by protocol sort by time Gene Expression Profile
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SampleTitleValueRank
GSM1340521parental biological replicate 11.920
GSM1340522parental biological replicate 23.326
GSM1340523DMSO 4h biological replicate 11.715
GSM1340524DMSO 4h biological replicate 22.424
GSM1340531DMSO 16h biological replicate 12.224
GSM1340532DMSO 16h biological replicate 23.933
GSM1340527MEKi 4h biological replicate 12.423
GSM1340528MEKi 4h biological replicate 20.46
GSM1340535MEKi 16h biological replicate 11.618
GSM1340536MEKi 16h biological replicate 22.222
GSM1340525TNKSi 4h biological replicate 11.921
GSM1340526TNKSi 4h biological replicate 2115
GSM1340533TNKSi 16h biological replicate 10.913
GSM1340534TNKSi 16h biological replicate 21.719
GSM1340529Combo 4h biological replicate 1430
GSM1340530Combo 4h biological replicate 2430
GSM1340537Combo 16h biological replicate 13.527
GSM1340538Combo 16h biological replicate 2221