ProfileGDS5029 / 222055_at
TitleSW480 KRAS-mutant colorectal cancer cell line response to dual inhibition of tankyrase and MEK: time course
OrganismHomo sapiens


untreated DMSO MEK inhibitor tankyrase inhibitor tankyrase and MEK inhibitors control 4 hours 16 hours 4 hours 16 hours 4 hours 16 hours 4 hours 16 hours GSM1340521 GSM1340522 GSM1340523 GSM1340524 GSM1340531 GSM1340532 GSM1340527 GSM1340528 GSM1340535 GSM1340536 GSM1340525 GSM1340526 GSM1340533 GSM1340534 GSM1340529 GSM1340530 GSM1340537 GSM1340538 45% 41% 46% 32% 53% 42% 48% 48% 48% 48% 49% 51% 48% 53% 52% 44% 45% 49% sort by protocol sort by time Gene Expression Profile
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SampleTitleValueRank
GSM1340521parental biological replicate 19.345
GSM1340522parental biological replicate 2841
GSM1340523DMSO 4h biological replicate 111.846
GSM1340524DMSO 4h biological replicate 24.132
GSM1340531DMSO 16h biological replicate 115.153
GSM1340532DMSO 16h biological replicate 2742
GSM1340527MEKi 4h biological replicate 113.548
GSM1340528MEKi 4h biological replicate 211.448
GSM1340535MEKi 16h biological replicate 112.748
GSM1340536MEKi 16h biological replicate 212.948
GSM1340525TNKSi 4h biological replicate 11249
GSM1340526TNKSi 4h biological replicate 215.151
GSM1340533TNKSi 16h biological replicate 11148
GSM1340534TNKSi 16h biological replicate 216.853
GSM1340529Combo 4h biological replicate 117.252
GSM1340530Combo 4h biological replicate 29.344
GSM1340537Combo 16h biological replicate 111.445
GSM1340538Combo 16h biological replicate 214.249