ProfileGDS5029 / 220124_at
TitleSW480 KRAS-mutant colorectal cancer cell line response to dual inhibition of tankyrase and MEK: time course
OrganismHomo sapiens


untreated DMSO MEK inhibitor tankyrase inhibitor tankyrase and MEK inhibitors control 4 hours 16 hours 4 hours 16 hours 4 hours 16 hours 4 hours 16 hours GSM1340521 GSM1340522 GSM1340523 GSM1340524 GSM1340531 GSM1340532 GSM1340527 GSM1340528 GSM1340535 GSM1340536 GSM1340525 GSM1340526 GSM1340533 GSM1340534 GSM1340529 GSM1340530 GSM1340537 GSM1340538 63% 62% 63% 66% 59% 62% 63% 65% 55% 56% 67% 64% 63% 63% 60% 59% 63% 63% sort by protocol sort by time Gene Expression Profile
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SampleTitleValueRank
GSM1340521parental biological replicate 143.263
GSM1340522parental biological replicate 239.662
GSM1340523DMSO 4h biological replicate 14563
GSM1340524DMSO 4h biological replicate 252.366
GSM1340531DMSO 16h biological replicate 127.159
GSM1340532DMSO 16h biological replicate 235.162
GSM1340527MEKi 4h biological replicate 147.263
GSM1340528MEKi 4h biological replicate 247.665
GSM1340535MEKi 16h biological replicate 123.355
GSM1340536MEKi 16h biological replicate 223.956
GSM1340525TNKSi 4h biological replicate 157.467
GSM1340526TNKSi 4h biological replicate 247.664
GSM1340533TNKSi 16h biological replicate 139.763
GSM1340534TNKSi 16h biological replicate 240.963
GSM1340529Combo 4h biological replicate 132.160
GSM1340530Combo 4h biological replicate 230.159
GSM1340537Combo 16h biological replicate 149.163
GSM1340538Combo 16h biological replicate 247.663