ProfileGDS5029 / 207466_at
TitleSW480 KRAS-mutant colorectal cancer cell line response to dual inhibition of tankyrase and MEK: time course
OrganismHomo sapiens


untreated DMSO MEK inhibitor tankyrase inhibitor tankyrase and MEK inhibitors control 4 hours 16 hours 4 hours 16 hours 4 hours 16 hours 4 hours 16 hours GSM1340521 GSM1340522 GSM1340523 GSM1340524 GSM1340531 GSM1340532 GSM1340527 GSM1340528 GSM1340535 GSM1340536 GSM1340525 GSM1340526 GSM1340533 GSM1340534 GSM1340529 GSM1340530 GSM1340537 GSM1340538 50% 45% 65% 58% 58% 58% 49% 50% 48% 49% 64% 63% 55% 53% 51% 55% 49% 46% sort by protocol sort by time Gene Expression Profile
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SampleTitleValueRank
GSM1340521parental biological replicate 114.250
GSM1340522parental biological replicate 210.345
GSM1340523DMSO 4h biological replicate 150.765
GSM1340524DMSO 4h biological replicate 224.958
GSM1340531DMSO 16h biological replicate 12458
GSM1340532DMSO 16h biological replicate 224.158
GSM1340527MEKi 4h biological replicate 114.649
GSM1340528MEKi 4h biological replicate 21350
GSM1340535MEKi 16h biological replicate 113.548
GSM1340536MEKi 16h biological replicate 213.949
GSM1340525TNKSi 4h biological replicate 14564
GSM1340526TNKSi 4h biological replicate 240.463
GSM1340533TNKSi 16h biological replicate 119.155
GSM1340534TNKSi 16h biological replicate 217.453
GSM1340529Combo 4h biological replicate 115.851
GSM1340530Combo 4h biological replicate 220.455
GSM1340537Combo 16h biological replicate 116.149
GSM1340538Combo 16h biological replicate 21246