ProfileGDS5029 / 205217_at
TitleSW480 KRAS-mutant colorectal cancer cell line response to dual inhibition of tankyrase and MEK: time course
OrganismHomo sapiens


untreated DMSO MEK inhibitor tankyrase inhibitor tankyrase and MEK inhibitors control 4 hours 16 hours 4 hours 16 hours 4 hours 16 hours 4 hours 16 hours GSM1340521 GSM1340522 GSM1340523 GSM1340524 GSM1340531 GSM1340532 GSM1340527 GSM1340528 GSM1340535 GSM1340536 GSM1340525 GSM1340526 GSM1340533 GSM1340534 GSM1340529 GSM1340530 GSM1340537 GSM1340538 82% 83% 87% 87% 87% 86% 81% 82% 84% 82% 86% 85% 85% 86% 81% 81% 82% 82% sort by protocol sort by time Gene Expression Profile
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SampleTitleValueRank
GSM1340521parental biological replicate 1265.982
GSM1340522parental biological replicate 2312.183
GSM1340523DMSO 4h biological replicate 1415.287
GSM1340524DMSO 4h biological replicate 2414.687
GSM1340531DMSO 16h biological replicate 1413.587
GSM1340532DMSO 16h biological replicate 2408.586
GSM1340527MEKi 4h biological replicate 1249.881
GSM1340528MEKi 4h biological replicate 2258.782
GSM1340535MEKi 16h biological replicate 1321.884
GSM1340536MEKi 16h biological replicate 226682
GSM1340525TNKSi 4h biological replicate 1395.286
GSM1340526TNKSi 4h biological replicate 234785
GSM1340533TNKSi 16h biological replicate 1358.285
GSM1340534TNKSi 16h biological replicate 2389.786
GSM1340529Combo 4h biological replicate 124381
GSM1340530Combo 4h biological replicate 2246.881
GSM1340537Combo 16h biological replicate 1290.382
GSM1340538Combo 16h biological replicate 2275.482