ProfileGDS5029 / 201790_s_at
TitleSW480 KRAS-mutant colorectal cancer cell line response to dual inhibition of tankyrase and MEK: time course
OrganismHomo sapiens


untreated DMSO MEK inhibitor tankyrase inhibitor tankyrase and MEK inhibitors control 4 hours 16 hours 4 hours 16 hours 4 hours 16 hours 4 hours 16 hours GSM1340521 GSM1340522 GSM1340523 GSM1340524 GSM1340531 GSM1340532 GSM1340527 GSM1340528 GSM1340535 GSM1340536 GSM1340525 GSM1340526 GSM1340533 GSM1340534 GSM1340529 GSM1340530 GSM1340537 GSM1340538 72% 71% 72% 74% 69% 70% 70% 72% 72% 73% 72% 71% 68% 70% 70% 74% 67% 69% sort by protocol sort by time Gene Expression Profile
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SampleTitleValueRank
GSM1340521parental biological replicate 1108.672
GSM1340522parental biological replicate 293.171
GSM1340523DMSO 4h biological replicate 1102.672
GSM1340524DMSO 4h biological replicate 2112.674
GSM1340531DMSO 16h biological replicate 171.969
GSM1340532DMSO 16h biological replicate 279.570
GSM1340527MEKi 4h biological replicate 187.470
GSM1340528MEKi 4h biological replicate 29572
GSM1340535MEKi 16h biological replicate 1103.172
GSM1340536MEKi 16h biological replicate 2122.673
GSM1340525TNKSi 4h biological replicate 1101.472
GSM1340526TNKSi 4h biological replicate 286.371
GSM1340533TNKSi 16h biological replicate 162.368
GSM1340534TNKSi 16h biological replicate 276.370
GSM1340529Combo 4h biological replicate 181.870
GSM1340530Combo 4h biological replicate 2123.574
GSM1340537Combo 16h biological replicate 172.967
GSM1340538Combo 16h biological replicate 278.969