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Sample GSM246718 Query DataSets for GSM246718
Status Public on Dec 06, 2007
Title MPR006743
Sample type RNA
 
Source name tumor sample
Organism Homo sapiens
Characteristics studyCode = 39
treatment = PS341
sex = Female
race = White
Age_at_Randomization = 80
Date_of_Randomization = 5-Jun-03
Myeloma_Measure = IGG
PGx_Response = IE
PGx_Responder = IE
PGx_CensorReason = No more data
Days_Survived_From_Randomization = 417
albumin = 41
C_Reactive_Protein = 4
Beta2_Microglobulin = 3.7
Number_of_Prior_Lines = 3
meanMyelScore = 32.03
Mayo_Clinic_ProliferativeIndex = 0.95
TC_Class_2006 = D1
Treatment protocol samples were subject to a rapid enrichment procedure (see details in http://bloodjournal.hematologylibrary.org/cgi/content/full/109/8/3177) and tumor cell pellet was frozen
Growth protocol tumor samples were collected during patient screening period prior to entry into clinical trials for the treatment of multiple myeloma
Extracted molecule total RNA
Extraction protocol Total RNA was isolated using Qiagen RNAeasy kit
Label biotin
Label protocol A standard T7 based amplification protocol (Affymetrix) was used to convert 2.0 microgram of RNA to biotinylated cRNA.
 
Hybridization protocol cRNA for each sample was hybridized in triplicate to the U133A/B array. Data represent median of replicates that passed array QC.
Scan protocol Microarrays were scanned with GeneArray 3000 scaner (Affymetrix).
Description Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib
Data processing Dataprocessing used Affymetrix MAS5.0.
 
Submission date Dec 04, 2007
Last update date Dec 05, 2007
Contact name George Mulligan
Organization name Millennium Pharmaceuticals
Department Clinical Development
Street address 35 Landsdowne Stree
City Cambridge
State/province MA
ZIP/Postal code 02139
Country USA
 
Platform ID GPL96
Series (1)
GSE9782 Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib

Data table header descriptions
ID_REF
VALUE MAS5 signal intensity

Data table
ID_REF VALUE
1007_s_at 119.871
1053_at 17.6878
117_at 69.3087
121_at 514.004
1255_g_at 29.1311
1294_at 345.049
1316_at 99.2508
1320_at 33.9904
1405_i_at 13.5297
1431_at 47.4808
1438_at 26.9403
1487_at 430.968
1494_f_at 183.443
1598_g_at 2528.41
160020_at 290.171
1729_at 37.5781
1773_at 11.1247
177_at 60.6025
179_at 534.631
1861_at 54.1231

Total number of rows: 22283

Table truncated, full table size 409 Kbytes.




Supplementary data files not provided
Processed data included within Sample table

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