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Sample GSM246559 Query DataSets for GSM246559
Status Public on Dec 06, 2007
Title MPM002224
Sample type RNA
 
Source name tumor sample
Organism Homo sapiens
Characteristics studyCode = 39
treatment = Dex
sex = Male
race = White
Age_at_Randomization = 77
Date_of_Randomization = 4-Dec-02
Myeloma_Measure = IGG
PGx_Response = NC
PGx_Responder = NR
PGx_CensorReason = No more data
Did_Patient_Die(0=No,1=Yes) = 1
Days_Survived_From_Randomization = 59
albumin = 35
C_Reactive_Protein = 4
Beta2_Microglobulin = 8.8
Number_of_Prior_Lines = 3
meanMyelScore = 31.56
Mayo_Clinic_ProliferativeIndex = 0.83918285
TC_Class_2006 = D1
Treatment protocol samples were subject to a rapid enrichment procedure (see details in http://bloodjournal.hematologylibrary.org/cgi/content/full/109/8/3177) and tumor cell pellet was frozen
Growth protocol tumor samples were collected during patient screening period prior to entry into clinical trials for the treatment of multiple myeloma
Extracted molecule total RNA
Extraction protocol Total RNA was isolated using Qiagen RNAeasy kit
Label biotin
Label protocol A standard T7 based amplification protocol (Affymetrix) was used to convert 2.0 microgram of RNA to biotinylated cRNA.
 
Hybridization protocol cRNA for each sample was hybridized in triplicate to the U133A/B array. Data represent median of replicates that passed array QC.
Scan protocol Microarrays were scanned with GeneArray 3000 scaner (Affymetrix).
Description Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib
Data processing Dataprocessing used Affymetrix MAS5.0.
 
Submission date Dec 04, 2007
Last update date Dec 05, 2007
Contact name George Mulligan
Organization name Millennium Pharmaceuticals
Department Clinical Development
Street address 35 Landsdowne Stree
City Cambridge
State/province MA
ZIP/Postal code 02139
Country USA
 
Platform ID GPL96
Series (1)
GSE9782 Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib

Data table header descriptions
ID_REF
VALUE MAS5 signal intensity

Data table
ID_REF VALUE
1007_s_at 195.832
1053_at 47.4145
117_at 42.3978
121_at 573.727
1255_g_at 27.0051
1294_at 242.311
1316_at 57.2135
1320_at 6.29825
1405_i_at 3.3257
1431_at 58.1698
1438_at 43.2502
1487_at 251.526
1494_f_at 145.188
1598_g_at 1559.86
160020_at 197.392
1729_at 240.237
1773_at 66.4305
177_at 31.7002
179_at 374.799
1861_at 77.1827

Total number of rows: 22283

Table truncated, full table size 409 Kbytes.




Supplementary data files not provided
Processed data included within Sample table

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