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| Status |
Public on Oct 25, 2016 |
| Title |
Role of Gq/11 and G12/13 signalling in Type II alveolar epithelial cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
We have used microarrays to identify individual genes and pathways regulated by Gq/11 or G12/13 signalling in type II alveolar epithelial cells isolated from the lungs of knockout mice.
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| |
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| Overall design |
Type II alveolar epithelial cells were isolated from the lungs of mice either singly deficient in Gna11 or Gna12 or double deficient in Gnaq/Gna11 or Gna12/Gna13 genes. Cells were cultured for 7 days and RNA processed from the untreated epithelial cells to compare gene expression patterns in cells from single and double knockout animals.
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| |
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| Contributor(s) |
John AE, Miele G |
| Citation(s) |
27811142 |
| |
| Submission date |
Oct 11, 2016 |
| Last update date |
Feb 11, 2019 |
| Contact name |
Alison Elizabeth John |
| E-mail(s) |
[email protected]
|
| Phone |
01158231106
|
| Organization name |
University of Nottingham
|
| Department |
Respiratory Medicine
|
| Street address |
Clinical Sciences Bulding, City Hospital Campus
|
| City |
Nottingham |
| State/province |
NOTTS |
| ZIP/Postal code |
NG5 1PB |
| Country |
United Kingdom |
| |
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| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA347839 |
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