|
| Status |
Public on Aug 22, 2017 |
| Title |
Expression data from Daxx knockout MEFs |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Neuroendocrine tumors (NETs) often harbor loss-of-function mutations in Daxx gene. Daxx interacts with several partners to regulate cellular processes and gene expression.
We used microarrays to detail the global gene expression change in Daxx knockout MEFs and identified up-regulated genes during this process.
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| |
|
| Overall design |
Daxx knockout mouse embryonic fibroblasts complemented with vector or Daxx were selected for RNA extraction and hybridization on Affymetrix microarrays. We sought to obtain downstream target genes regulated by Daxx.
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| |
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| Contributor(s) |
Feng Z, Hua X |
| Citation(s) |
27872097 |
| |
| Submission date |
Oct 07, 2016 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Xianxin Hua |
| E-mail(s) |
[email protected]
|
| Organization name |
University of Pennsylvania Perelman School of Medicine
|
| Department |
Department of Cancer Biology
|
| Lab |
Hua Lab
|
| Street address |
421 Curie BLVD
|
| City |
philadelphia |
| State/province |
PA |
| ZIP/Postal code |
19104 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (8)
|
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| Relations |
| BioProject |
PRJNA347288 |
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