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Status |
Public on Jul 31, 2017 |
Title |
Silencing SMOC2 protects from kidney fibrosis by inhibiting Fibroblast to Myofibroblast Transformation |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
|
Summary |
Secreted MOdular Calcium-binding protein-2 (SMOC2) belongs to the SPARC (Secreted Protein Acidic and Rich in Cysteines) family of matricellular proteins whose members are known for their secretion into the extracellular space to modulate cell-cell and cel
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Overall design |
mRNA sequencing of mouse kidney of wildtype and Smoc2 transgenic mice with and without 7 day unilateral uretal obstruction intervention
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Contributor(s) |
Gerarduzzi C, Vaidya VS, Hutchinson JN |
Citation(s) |
28422762 |
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Submission date |
Aug 04, 2016 |
Last update date |
May 15, 2019 |
Contact name |
John N Hutchinson |
Organization name |
Harvard Chan School of Public Health
|
Street address |
677 Huntington Avenue
|
City |
Boston |
State/province |
Massachusetts |
ZIP/Postal code |
02215 |
Country |
USA |
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Platforms (1) |
GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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Samples (14)
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Relations |
BioProject |
PRJNA336552 |
SRA |
SRP080947 |