|
| Status |
Public on Dec 07, 2016 |
| Title |
Identification of PTBPs RNA binding sites in mouse brain |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
PTBP1 and PTBP2 are RNA-binding proteins that control RNA processings, including alternative pre-mRNA splicing. The sequential down-regulation of the two proteins is necessary for neuronal maturation. However, their binding substrates in neural tissues have not been examined.
|
| |
|
| Overall design |
Use modified version of iCLIP-seq protocols to identify RNA elements crosslinked to either flag-PTBP1 or PTBP2 in vivo in the mouse cerebral cortex.
|
| |
|
| Contributor(s) |
Zheng S, Lin CH |
| Citation(s) |
27926877 |
| |
| Submission date |
Aug 03, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Chia-ho Lin |
| E-mail(s) |
[email protected]
|
| Organization name |
UCLA
|
| Lab |
BLACK LAB
|
| Street address |
6577 MRL. 675 CHARLES E YOUNG DR. SOUTH
|
| City |
LOS ANGELES |
| State/province |
CA |
| ZIP/Postal code |
90095 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA336372 |
| SRA |
SRP080878 |
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