|
| Status |
Public on Sep 01, 2017 |
| Title |
Global gene expression profiles of induced lung progenitor (iLung) cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
We generated mouse embryonic and adult fibroblasts into lung progenitor-like cells by defined transcription factors. To evaluate characteristic of iLung cell, we compared the global gene expression profiles of iLung cells with those of mouse embryonic fibroblasts (MEFs), mouse dermal fibroblasts (MDFs), adult trachea, lung, esophagus, thyroid and E11.5 embryonic lung cells using microarrays.
|
| |
|
| Overall design |
MEFs were prepared from E13.5 mouse dorsal skin and limb skin. For MDFs preparation, skin tissue behind the ear of 12 week old mice was used. iLung cells were generated by retroviral transduction of transcription factors. In addition we also extracted total RNA form the trachea, lung, esophagus, and thyroid tissues isolated from 8 week old mice.
|
| |
|
| Contributor(s) |
Ninomiya N, Noguchi TK, Sekine M, Kurisaki A |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Sep 01, 2015 |
| Last update date |
Sep 02, 2017 |
| Contact name |
Naoto Ninomiya |
| E-mail(s) |
[email protected]
|
| Organization name |
National Institute of Advanced Industrial Science and Technology
|
| Department |
Biotechnology Research Institute for Drug Discovery
|
| Lab |
Stem Cell Engineering Research Group
|
| Street address |
1-1-1 Higashi
|
| City |
Tsukuba |
| State/province |
Ibaraki |
| ZIP/Postal code |
305-8565 |
| Country |
Japan |
| |
|
| Platforms (1) |
| GPL7202 |
Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version) |
|
| Samples (23)
|
|
| Relations |
| BioProject |
PRJNA294433 |
Less...
More...