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| Status |
Public on Jun 18, 2015 |
| Title |
Placental changes caused by food restriction during early pregnancy in mice are reversible |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
In a previous study, 50% calorie restriction in mice from days 1.5-11.5 of pregnancy resulted in reduced placental weights and areas, relatively sparing of labyrinth zone area compared to junctional zone area, and dramatic changes in global gene expression profiles. Here we examined placental gene expression at day 18.5, after the return to normal feeding to see whether differences were reversible
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| Overall design |
Mice were randomized to 2 treatment groups on day 1.5 of pregnancy: (1) ad libitum fed (control) (2) 50% food restriction (restricted). Mice were returned to ad libitum feed on d11.5, sacrificed on d18.5 and placentas were collected.
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| Contributor(s) |
Schulz LC |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jun 17, 2015 |
| Last update date |
Nov 01, 2017 |
| Contact name |
Laura Clamon Schulz |
| E-mail(s) |
[email protected]
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| Organization name |
University of Missouri
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| Department |
Obstetrics, Gynecology and Women's Health
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| Street address |
1 Hospital Dr.
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| City |
Columbia |
| State/province |
MO |
| ZIP/Postal code |
65212 |
| Country |
USA |
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| Platforms (1) |
| GPL11202 |
Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Probe Name version) |
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| Samples (10)
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| Relations |
| BioProject |
PRJNA287218 |
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