|
| Status |
Public on May 21, 2015 |
| Title |
Role of histone demethylase LSD1 in hepatic cancer metabolism |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Transcriptome analysis of LSD1-depleted HepG2 cells revealed that LSD1 regulates the expression of glycolytic and mitochondrial metabolism genes.
We found that LSD1 is an important regulator of glycolysis and mitochondrial respiration in hepatoma.
|
| |
|
| Overall design |
We depleted LSD1 in HepG2 human hepatoma cells using two different siRNAs, and then carried out an expression microarray experiment.
|
| |
|
| Contributor(s) |
Sakamoto A, Hino S, Nakao M |
| Citation(s) |
25649769 |
| |
| Submission date |
May 20, 2015 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Akihisa Sakamoto |
| Organization name |
Kumamoto University
|
| Department |
Institute of Molecular Embryology and Genetics
|
| Lab |
Department of Medical Cell Biology
|
| Street address |
2-2-1 Honjo, Chuo-ku
|
| City |
Kumamoto |
| ZIP/Postal code |
860-0811 |
| Country |
Japan |
| |
|
| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
|
| Samples (4)
|
|
| Relations |
| BioProject |
PRJNA284489 |
Less...
More...