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| Status |
Public on Aug 28, 2014 |
| Title |
Epigenetic silencing of SFRP4 contributes to epidermal hyperplasia in psoriasis |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
To investigate the gene expression of imiquimod induced psoriasis-like mouse model, we have employed whole genome microarray as a discovery platform to identify genes differentially expressed compared with wild type C57BL6 mouse exposed to the vehicle of imiquimod.
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| Overall design |
C57BL/6J mice at 6 to 8 weeks of age were applied to a daily topical dose of 62.5 mg of IMQ cream (5%) on the shaved back for 7 consecutive days. Control mice were treated with a same dose of vehicle cream.The total RNA was extracted by using TRIzol.
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| Contributor(s) |
Wang H, Bai J |
| Citation(s) |
25825452 |
| |
| Submission date |
Aug 27, 2014 |
| Last update date |
Jan 08, 2018 |
| Contact name |
Hong Lin Wang |
| Organization name |
Shanghai Jiao Tong University
|
| Street address |
280 Chongqing South Road
|
| City |
Shanghai |
| ZIP/Postal code |
200025 |
| Country |
China |
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| Platforms (1) |
| GPL7202 |
Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA259596 |
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