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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Aug 01, 2014 |
| Title |
NF-kB in Tumor Initiation |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
p65-/-Ras cells show delayed tumor formation in SCID mice. However, after prolonged latency, tumor formation was observed from these mice. To understand the changes of NF-kB regulated genes before and after tumor formation, RNA from p65+/+Ras, p65+/+RasTumor, p65-/-Ras, p65-/-RasTumor cells were isolated and microarray were performed.
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| Overall design |
p65+/+Ras and p65-/-Ras cells were injected into SCID mice. Tumors were removed and put back into tissue culture. RNA was isolated from these cells and microarrays were performed.
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| Contributor(s) |
Wang DJ, Ratnam N, Guttridge D, Byrd J |
| Citation(s) |
25263557 |
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| Submission date |
Jul 17, 2014 |
| Last update date |
Feb 11, 2019 |
| Contact name |
David Jingxin Wang |
| E-mail(s) |
[email protected]
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| Phone |
6146884507
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| Organization name |
The Ohio State University
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| Department |
Comprehensive Cancer Center
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| Lab |
Guttridge Lab
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| Street address |
BRT536, 460w, 12th Ave.
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| City |
Columbus |
| State/province |
Ohio |
| ZIP/Postal code |
43210 |
| Country |
USA |
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| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA255634 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE59545_RAW.tar |
40.0 Mb |
(http)(custom) |
TAR (of CEL, DCP, TXT) |
| GSE59545_log2_ratios.txt.gz |
393.2 Kb |
(ftp)(http) |
TXT |
| Processed data included within Sample table |
| Processed data are available on Series record |
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