|
| Status |
Public on Jul 09, 2014 |
| Title |
Gene expression profiles of PDX models with acquired resistance to endocrine treatments |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Acquired resistance to endocrine therapy occurs with high frequency in patients with luminal breast cancer (LBC). We report here the establishment of four patient-derived xenograft models of LBC with acquired resistance in vivo to tamoxifen and estrogen deprivation.
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| |
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| Overall design |
CEL files represent expresison data generated from 5 replicates (independent mice) of the following tumor models: HBCx22 (parental), HBCx22 TamR (tamoxifen-resistant), HBCx22 OvaR (ovariectomy-resistant), HBCx34 (parental), HBCx34 TamR (tamoxifen-resistant), HBCx34 OvaR (ovariectomy-resistant)
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| |
|
| Contributor(s) |
Marangoni E |
| Citation(s) |
24947930 |
| |
| Submission date |
Mar 04, 2014 |
| Last update date |
Nov 08, 2016 |
| Contact name |
Pierre de la Grange |
| E-mail(s) |
[email protected]
|
| Organization name |
GenoSplice technology
|
| Department |
Paris Biotech Santé
|
| Street address |
29, rue du Faubourg Saint-Jacques
|
| City |
Paris |
| ZIP/Postal code |
75014 |
| Country |
France |
| |
|
| Platforms (1) |
| GPL11532 |
[HuGene-1_1-st] Affymetrix Human Gene 1.1 ST Array [transcript (gene) version] |
|
| Samples (30)
|
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| Relations |
| BioProject |
PRJNA239992 |
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