|
| Status |
Public on May 07, 2016 |
| Title |
Role of smooth muscle cell autophagy in atherosclerosis |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Study of the effect of autophagy inhibition on smooth muscle cell function and atherosclerotic plaque stability
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| |
|
| Overall design |
The study searches for differences in gene expression in SMCs from the aorta of mice between two mouse strains (Atg7+/+ SM22α-Cre+ and Atg7F/F SM22α-Cre+). For each strain, two biological replicates were collected. The cells were cultured in DMEM/F-12 medium supplemented with 10% FBS. Cells from passage 4 untill 10 were used for experiments. Two-color arrays were run, each time comparing a replicate from one strain to a replicate from the other strain. For each array we added a dye swap, giving a total of four arrays.
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| |
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| Contributor(s) |
Grootaert MO, Martinet W, Schrijvers DM |
| Citation(s) |
26391655 |
| |
| Submission date |
Jan 13, 2014 |
| Last update date |
Jan 12, 2017 |
| Contact name |
Rekin's Janky |
| E-mail(s) |
[email protected]
|
| Organization name |
VIB
|
| Department |
Nucleomics Core
|
| Street address |
Herestraat 49 Box 816
|
| City |
Leuven |
| ZIP/Postal code |
B-3000 |
| Country |
Belgium |
| |
|
| Platforms (1) |
| GPL7202 |
Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version) |
|
| Samples (4)
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|
| Relations |
| BioProject |
PRJNA234362 |
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