|
| Status |
Public on Aug 20, 2013 |
| Title |
Effect of Twist-box mutation on gene expression induced by Twist1 overexpression |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Twist1 is a transcription factor that induces EMT and drives metastasis in prostate cancer. We examined global gene expression in Myc-CaP mouse prostate cancer cells following overexpression
of Twist1 and the Twist1 mutants F191G, AQA, and DQD.
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| |
|
| Overall design |
15 total samples were analysed, with 3 replicates of 5 groups: Twist1-WT, Twist1-AQA, Twist1-DQD, Twist1-F191G, and vector control. We performed the comparisons: WT > VEC, F191G > VEC. Samples were normalized by Twist1 expression in addition to normal
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| |
|
| Contributor(s) |
Gajula R, Tran P |
| Citation(s) |
23982216 |
| |
| Submission date |
Aug 19, 2013 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Russell Williams |
| E-mail(s) |
[email protected]
|
| Organization name |
Johns Hopkins University
|
| Department |
Radiation Oncology
|
| Lab |
Tran
|
| Street address |
1550 Orleans St
|
| City |
Baltimore |
| State/province |
MD |
| ZIP/Postal code |
21231 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
|
| Samples (15)
|
|
| Relations |
| BioProject |
PRJNA215782 |
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