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| Status |
Public on Jun 12, 2016 |
| Title |
Drosophila melanogaster Show a Threshold Effect in Response to Radiation |
| Organism |
Drosophila melanogaster |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
We investigate the biological effects of radiation using Drosophila Melanogaster as a model organism, focusing on gene expression and lifespan analysis to determine the effect of different radiation doses. Our results support a threshold effect in response to radiation: no effect on lifespan and no permanent effect on gene expression is seen at doses below 10,000 Roentgens.
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| Overall design |
Adult male Drosophila were irradiated 2 days after eclosion, with one of 6 radiation doses: 10; 1,000; 5,000; 10,000; 20,000 Roentgens. Samples were taken at 3 time points (2, 10 and 20 days post-irradiation).
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| Contributor(s) |
Antosh M, Neretti N |
| Citation(s) |
25552957 |
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| Submission date |
Jun 17, 2013 |
| Last update date |
May 15, 2019 |
| Contact name |
Michael Antosh |
| Organization name |
Michael Antosh
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| Street address |
Brown University Box 1843
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| City |
Providence |
| State/province |
RI |
| ZIP/Postal code |
02912 |
| Country |
USA |
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| Platforms (1) |
| GPL13304 |
Illumina HiSeq 2000 (Drosophila melanogaster) |
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| Samples (53)
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| GSM1164656 |
Control Day 10, Rep 1 |
| GSM1164657 |
Control Day 10, Rep 2 |
| GSM1164658 |
Control Day 10, Rep 3 |
| GSM1164659 |
Control Day 20, Rep 1 |
| GSM1164660 |
Control Day 20, Rep 2 |
| GSM1164661 |
10 R Day 2, Rep 1 |
| GSM1164662 |
10 R Day 2, Rep 2 |
| GSM1164663 |
10 R Day 2, Rep 3 |
| GSM1164664 |
10 R Day 10, Rep 1 |
| GSM1164665 |
10 R Day 10, Rep 2 |
| GSM1164666 |
10 R Day 10, Rep 3 |
| GSM1164667 |
10 R Day 20, Rep 1 |
| GSM1164668 |
10 R Day 20, Rep 2 |
| GSM1164669 |
10 R Day 20, Rep 3 |
| GSM1164670 |
1,000 R Day 2, Rep 1 |
| GSM1164671 |
1,000 R Day 2, Rep 2 |
| GSM1164672 |
1,000 R Day 2, Rep 3 |
| GSM1164673 |
1,000 R Day 10, Rep 1 |
| GSM1164674 |
1,000 R Day 10, Rep 2 |
| GSM1164675 |
1,000 R Day 10, Rep 3 |
| GSM1164676 |
1,000 R Day 20, Rep 1 |
| GSM1164677 |
1,000 R Day 20, Rep 2 |
| GSM1164678 |
1,000 R Day 20, Rep 3 |
| GSM1164679 |
5,000 R Day 2, Rep 1 |
| GSM1164680 |
5,000 R Day 2, Rep 2 |
| GSM1164681 |
5,000 R Day 2, Rep 3 |
| GSM1164682 |
5,000 R Day 10, Rep 1 |
| GSM1164683 |
5,000 R Day 10, Rep 2 |
| GSM1164684 |
5,000 R Day 10, Rep 3 |
| GSM1164685 |
5,000 R Day 20, Rep 1 |
| GSM1164686 |
5,000 R Day 20, Rep 2 |
| GSM1164687 |
5,000 R Day 20, Rep 3 |
| GSM1164688 |
10,000 R Day 2, Rep 1 |
| GSM1164689 |
10,000 R Day 2, Rep 2 |
| GSM1164690 |
10,000 R Day 2, Rep 3 |
| GSM1164691 |
10,000 R Day 10, Rep 1 |
| GSM1164692 |
10,000 R Day 10, Rep 2 |
| GSM1164693 |
10,000 R Day 10, Rep 3 |
| GSM1164694 |
10,000 R Day 20, Rep 1 |
| GSM1164695 |
10,000 R Day 20, Rep 2 |
| GSM1164696 |
10,000 R Day 20, Rep 3 |
| GSM1164697 |
20,000 R Day 2, Rep 1 |
| GSM1164698 |
20,000 R Day 2, Rep 2 |
| GSM1164699 |
20,000 R Day 2, Rep 3 |
| GSM1164700 |
20,000 R Day 10, Rep 1 |
| GSM1164701 |
20,000 R Day 10, Rep 2 |
| GSM1164702 |
20,000 R Day 10, Rep 3 |
| GSM1164703 |
20,000 R Day 20, Rep 1 |
| GSM1164704 |
20,000 R Day 20, Rep 2 |
| GSM1164705 |
20,000 R Day 20, Rep 3 |
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| Relations |
| BioProject |
PRJNA208624 |
| SRA |
SRP026086 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE47999_Normalized_Counts.txt.gz |
3.8 Mb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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