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Series GSE47560 Query DataSets for GSE47560
Status Public on Jun 21, 2013
Title Leukemia associated mutant Wilms' tumour gene 1 protein promotes expansion of human hematopoietic progenitor cells
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Analysis of gene expression levels in hematopoietic progenitor cells retrovirally transduced with full-length WT1(+/-) or a WT1-mutant lacking zinc-finger, WT1(delZ) cultured in vitro for 14 days. The hypothesis tested in this study was that the WT1-mutant confers an increased proliferation rate after 14 days in culture and an erythroid phenotype. Results provide information of upregulation of some genes associated with cellcycle progression, upregulated genes connected with erythropoiesis and downmodulation of some genes associated with myeloid differentiation.
 
Overall design Total RNA obtained from CD34+ progenitor cells in suspension cultures for 14 days.
 
Contributor(s) Vidovic K, Ullmark T, Rosberg B, Olofsson T, Lennartsson A, Nilsson B, Gullberg U
Citation(s) 23871158
Submission date May 31, 2013
Last update date Aug 13, 2018
Contact name Karina Vidovic
Organization name Lund University
Department Hematology and Transfusion Medicine
Lab UG-group
Street address Klinikgatan 26
City Lund
ZIP/Postal code 221 84
Country Sweden
 
Platforms (1)
GPL10558 Illumina HumanHT-12 V4.0 expression beadchip
Samples (11)
GSM1152463 Control rep1
GSM1152464 Control rep2
GSM1152465 Control rep3
Relations
BioProject PRJNA206072

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE47560_RAW.tar 26.2 Mb (http)(custom) TAR
GSE47560_non_normalized.txt.gz 3.4 Mb (ftp)(http) TXT
Processed data included within Sample table

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