|
| Status |
Public on May 23, 2014 |
| Title |
BCR-ABL1 and a dominant negative isoform of Ikaros cooperate to induce human acute myeloid leukemia |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Analysis of lineage depleted human cord blood cells sequentially transduced with retro- (BCR-ABL1) and lentiviral (Ik6) vectors and the corresponding controls. Results provide important informations on the collaboration of BCR-ABL1 and Ik6 in human hematopoietic cells.
|
| |
|
| Overall design |
Double-transduced lineage depleted human cord blood cells were puirifed according to GFP and LNGFR expression. RNA was extracted from purified cells.
|
| |
|
| Contributor(s) |
Theocharides AP, Laurenti E, Dobson S, Dick JE |
| Citation(s) |
24791856 |
| |
| Submission date |
Mar 24, 2013 |
| Last update date |
Aug 13, 2018 |
| Contact name |
Elisa Laurenti |
| Organization name |
University of Cambridge
|
| Department |
Haematology
|
| Lab |
Laurenti laboratory
|
| Street address |
Jeffrey Cheah Biomedical Centre
|
| City |
Cambridge |
| ZIP/Postal code |
CB2 0AW |
| Country |
United Kingdom |
| |
|
| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
|
| Samples (16)
|
|
| Relations |
| BioProject |
PRJNA194068 |
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