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| Status |
Public on Mar 20, 2013 |
| Title |
Transcriptional profiles of kidneys that underwent reversible UUO model using model mice for erythropoietin-deficiency anemia (ISAM) |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
We have established a novel mouse model for postnatal erythropoietin (Epo)-deficiency anaemia, designated ISAM (inherited super anemic mouse) using a transgenic complementation rescue technique. To identify responsible signals for myofibroblastic transformation of Renal Erythropoietin-producing cells (REPs), we examined the mRNA expression profile of whole ISAM kidneys that underwent reversible UUO model.
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| Overall design |
Unilateral ureteral obstruction (UUO)-induced gene expression changes were analyzed. Three UUO-treated samples (Clip), three reversed UUO kidneys (ClipR-14), and two sham-treated and one untreated samples were compared.
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| Contributor(s) |
Souma T, Yamazaki S, Moriguchi T, Suzuki N, Yamamoto M |
| Citation(s) |
23833259 |
| |
| Submission date |
Mar 19, 2013 |
| Last update date |
Jan 12, 2017 |
| Contact name |
Masayuki Yamamoto |
| E-mail(s) |
[email protected]
|
| Phone |
81-22-717-8084
|
| Organization name |
Tohoku University Graduate School of Medicine
|
| Department |
Medical Biochemistry
|
| Street address |
2-1 Seiryo-machi, Aoba-ku
|
| City |
Sendai |
| ZIP/Postal code |
980-8575 |
| Country |
Japan |
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| Platforms (1) |
| GPL7202 |
Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version) |
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| Samples (9)
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| Relations |
| BioProject |
PRJNA193435 |
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