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| Status |
Public on Feb 01, 2013 |
| Title |
Expression data from WT and E2A-deficient murine DN2 cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
The E2A transcription factors promote the development of thymus-seeding cells but it remains unknown whether these proteins play a role in T lymphocyte lineage specification or commitment. By examining E2A-dependent genes in developing T cells, we will address whether these proteins are involved in these processes.
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| |
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| Overall design |
DN2 cells from WT and E2A-deficient murine fetal thymi were FACS sorted. Subsequently RNA was extracted, labelled and hybridized to Affymetrix microarrays. The goal of this study is to investigate E2A-dependent genes in developing T cells
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| |
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| Contributor(s) |
Xu W, Carr T, Ramirez K, McGregor S, Sigvardsson M, Kee B |
| Citation(s) |
23297135 |
| |
| Submission date |
Dec 31, 2012 |
| Last update date |
Feb 11, 2019 |
| Contact name |
Barbara Kee |
| Organization name |
University of Chicago
|
| Department |
Pathology
|
| Lab |
Kee
|
| Street address |
924 East 57th Street
|
| City |
Chicago |
| State/province |
IL |
| ZIP/Postal code |
60637 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
|
| Samples (6)
|
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| Relations |
| BioProject |
PRJNA185009 |
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