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| Status |
Public on Apr 05, 2013 |
| Title |
Gene signature of young and replicative senescent human umbilical vein endothelial cells (HUVECs) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
MicroRNAs regulate various cellular processes. While several genes associated with replicative senescence have been described in endothelial cells, miRNAs that regulate these genes remain largely unknown. The present study was designed to identify miRNAs associated with replicative senescence and their target genes in HUVECs. Gene profiling was established using the same RNA input as that used for miRNA profiing. We have employed Agilent Whole Human Genome microarray platform to evaluate the expressions of 19,596 human genes .
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| Overall design |
Gene expression profiles were established for young and replicative senescent HUVECs
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| Contributor(s) |
Jong H, Mustafa MR, Vanhoutte PM, AbuBakar S, Wong P |
| Citation(s) |
23362143 |
| |
| Submission date |
Apr 06, 2012 |
| Last update date |
Jan 23, 2019 |
| Contact name |
Pooi-Fong Wong |
| Organization name |
University of malaya
|
| Department |
Pharmacology
|
| Street address |
Faculty of Medicine
|
| City |
KUALA LUMPUR |
| ZIP/Postal code |
50603 |
| Country |
Malaysia |
| |
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| Platforms (1) |
| GPL6480 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version) |
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| Samples (5)
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| This SubSeries is part of SuperSeries: |
| GSE37093 |
MicroRNA and Gene signatures of young and replicative senescent human umbilical vein endothelial cells |
|
| Relations |
| BioProject |
PRJNA158115 |
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